Chiefs RB Isiah Pacheco Diagnosed with MCL Sprain, Listed as Week-to-Week

Kansas City Chiefs Running Back Isiah Pacheco Sidelined with Knee Injury

The Kansas City Chiefs received confirmation regarding the status of their primary running back, Isiah Pacheco, following his exit from Monday night’s victory. According to reporting from Tom Pelissero of NFL Media, Pacheco has been diagnosed with an MCL sprain and has been given a week-to-week designation.

This news confirms that the Chiefs will be without their leading rusher for at least the immediate future, forcing a significant shift in the team’s offensive game plan and backfield rotation as they navigate the critical mid-to-late stages of the season.


Understanding the MCL Sprain and Recovery Timeline

The medial collateral ligament (MCL) is crucial for stabilizing the knee joint, particularly against lateral stress—a frequent occurrence for running backs who rely on cutting and changing direction. A “week-to-week” status typically suggests a Grade 1 or low-end Grade 2 sprain, avoiding the need for surgery but requiring careful management.

For a player like Pacheco, whose running style is defined by aggressive, high-contact bursts, the focus during recovery will be regaining full lateral stability and confidence in the knee. While specific return timelines vary greatly depending on the severity and the player’s response to treatment, the week-to-week designation implies:

  • Absence: Pacheco is highly unlikely to play in the upcoming game(s).
  • Rehabilitation: Treatment will focus on reducing swelling, restoring range of motion, and strengthening the surrounding musculature.
  • Return: A return could potentially occur in 2 to 4 weeks, though the Chiefs will prioritize his long-term health and playoff availability over rushing him back.

This injury is a substantial blow, as Pacheco has been the engine of the Chiefs’ running game, providing necessary balance to the high-powered passing attack.


Immediate Impact on the Chiefs’ Backfield Depth

Pacheco’s absence immediately elevates the roles of the remaining running backs on the roster. The Chiefs are known for utilizing a committee approach, but Pacheco had clearly established himself as the lead back for early downs and goal-line situations.

The Revised Running Back Rotation

The Chiefs’ coaching staff will now rely heavily on their veteran depth to manage the rushing workload:

  • Clyde Edwards-Helaire (CEH): Edwards-Helaire, a former first-round pick, is the most likely candidate to assume the primary early-down and rushing role. He offers a different style than Pacheco, emphasizing quickness and receiving ability, but will need to handle a heavier volume of carries.
  • Jerick McKinnon: McKinnon remains the team’s trusted third-down and receiving specialist. His veteran presence and pass-blocking prowess are invaluable, especially in high-leverage situations. His role is unlikely to change significantly, but his snap count might increase slightly.
  • Potential Depth Options: Depending on the severity of Pacheco’s absence, the team may activate practice squad members or look to free agency for experienced depth to manage the wear and tear on CEH and McKinnon.

“The key for the Chiefs now is load management. They need Edwards-Helaire to stay healthy and McKinnon to continue providing reliable third-down production without overextending either player in Pacheco’s absence,” noted one league analyst.


Roster Strategy and Context

While the NFL trade deadline may have passed, the injury forces the Chiefs to evaluate their roster depth critically. The initial report mentioning the need for depth underscores the team’s awareness of the fragility of the running back position.

If Pacheco’s recovery extends beyond the initial 3-4 week projection, the Chiefs may explore the veteran free agent market for a reliable, low-cost option who can contribute immediately. However, given the week-to-week status, the more probable scenario is relying on the current personnel and utilizing the versatility of their offense, potentially leaning more heavily on quarterback runs and short passing concepts to compensate for the lost rushing production.

This situation also highlights the importance of the Chiefs’ offensive line performance. Without Pacheco’s ability to break tackles and gain yards after contact, the line will face increased pressure to create larger running lanes for Edwards-Helaire.


Key Takeaways for Chiefs Fans and Fantasy Managers

  • Injury Confirmation: Isiah Pacheco has an MCL sprain.
  • Status: He is officially week-to-week.
  • Immediate Replacement: Clyde Edwards-Helaire is expected to take over the majority of the rushing workload.
  • Specialist Role: Jerick McKinnon will maintain his crucial role as the primary receiving and third-down back.
  • Outlook: The Chiefs will likely manage Pacheco’s return carefully to ensure he is fully healthy for the postseason push.

What’s Next

The Chiefs will provide daily updates on Pacheco’s rehabilitation progress. The immediate focus will be on their next opponent and how the newly structured backfield committee performs. The performance of Edwards-Helaire over the next two games will be critical in determining whether the Chiefs feel comfortable with their internal depth or if they must make an external roster move to secure additional insurance at the position.

Original author: Myles Simmons

Originally published: October 28, 2025

Editorial note: Our team reviewed and enhanced this coverage with AI-assisted tools and human editing to add helpful context while preserving verified facts and quotations from the original source.

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  • Eduardo Silva is a Full-Stack Developer and SEO Specialist with over a decade of experience. He specializes in PHP, WordPress, and Python. He holds a degree in Advertising and Propaganda and certifications in English and Cinema, blending technical skill with creative insight.

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